![]() ![]() The activity of the extract against the venom induced mortality, occurrence of toxic signs, activity on liver enzymes as well as its ability to reverse experimentally induced increase in body temperature were evaluated. The extract was also tested on brine shrimp (Artemia saline Leach). The researchers noted: “The potency of the methanol extract of the root bark of the plant was tested against cobra (Naja nigricotlis nigricotlis Wetch) venom in rats. The study titled “Effects of aqueous root extract of Annona senegalensis on Bitisarietans venom protease and phospholipase A2 activities” was published in the Journal of Pharmacology and Biomedical Sciences.Īnother study published in the Journal Ethnopharmacology has demonstrated the effect of Annona senegalensis root bark extracts on Naja nigricotlis nigricotlis venom in rats. The researchers from Department of Biochemistry, Faculty of Science, University of Maiduguri, Borno State, found that the root extract of Annona senegalensis possesses potent snake venom neutralising capacity and may provide protection against the toxicity posed by the Bitisarietans venom and could be used for therapeutic purposes in case of snakebite. In Nigeria, it is called umm boro in Arabic-Shuwa ewura in Berom boili in Fula-Fulfulde ououd on Goemai kmijirihi in Gwari gwándàr daájiì and tàllàfà màraàyú in Hausa uwu in Idoma ukpokpo in Igala uburu-ọcha in Ibo ngónówù in Kanuri oguoto in Yekhee àbo and arere in Yoruba.Ī recent study has scientifically validated the folklore use of Annona senegalensis in the treatment of snakebite by the farmers and herdsmen in Northern Nigeria. Top on the list are: English wild custard apple (Annona senegalensis), Velvet bean or Cowhage (Mucuna pruriens), Turmeric (Curcuma longa), Plantain (Musa paradiasica).Ĭommonly called English wild custard apple, Annona senegalensis belongs to the plant family Annonaceae. However, scientists have recently validated some local plant as herbal medicines for snakebite management. But till date no such drugs are available in the market, which possess anti snake venom activity. There are various medicinal plants, which have been used in folk and traditional medicines against snakebites especially among the Fulani herdsmen of Northern Nigeria. AVS administration is often associated with hypersensitivity reactions (early and late), which need further medical attention. Snake venom antiserum or AVS has administration problem, the exact dosage is also a current problem. Further, due to its storage difficulty and short expiry, its use is restricted. Due to its high cost and lack of availability of antisera makes it difficult for the rural patients to access. But the usage of snake venom antisera has its own drawbacks. ![]()
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